Pharmaco​genomics.
Really.

Our genomic+metabolic AI foundation models
learn human biology from large clinical study datasets,
enabling high precision predictions
about how individuals will respond to a drug,
how they can reduce disease risk,
and extend their lifespan and healthspan.

Until now, truly predictive GxEs were elusive:

  • GxEs (gene-environment interactions) are complex. Tens, hundreds, even thousands of SNPs (Single Nucleotide Polymorphisms) can be significant in predicting each interaction.
  • Current methodologies, such as genome-wide associations (GWAS), miss so many SNPS that they cannot predict response for most GxEs.

  • Genteract’s new genetic discovery methodologies find a much greater fraction of the SNPs in each GxE and generates accurate GxE predictions. 

 

Conventional Analysis

Traditional techniques find no significant change in this population’s phenotype with increasing exposure to a drug or other environmental factor.

Genteract Analysis

Genteract’s novel unsupervised analytical systems biology methodology detects genetically-defined sub-groups within the population who respond differently to the drug or other environmental factor, and discovers all the SNPs that are significant in this difference.

We use the output of our patented genetic discovery method, along with medical data to train an AI foundation model to make accurate biomedical predictions.

Genteract Methodology

Insights learned from each clinical dataset are portable– they improve foundation model performance for every subsequent predictive task because each dataset increases the model’s understanding of human biology.

GxE Applications

Just a few of them.

Drug Response Prediction

Deliver cost savings for payers and improved quality of care by predicting which drugs will work the best, with the fewest side effects, for each patient.

Clinical Trial Optimization and Drug Repositioning

Identify genetically-defined patient subgroups who respond differently to a drug, including new indications for existing drugs.

Drug Approvals

Rescue drugs rejected by the FDA in phase III due to lack of broad efficacy, through a test that identifies patients who are strong responders.

Disease Risk and Mitigation

Determine a patient's risk of diseases and find pharmaceutical and nutritional interventions to mitigate that risk.

Partner with Us

The clinical trial or EMR data you already have may have massive hidden value that Genteract Analysis can unlock. 

Contact us now to discuss a no-obligation analysis of your data to create highly accurate  GxE predictions with cross-validation.